Aluminum–phthalocyanine chloride associated to poly(methyl vinyl ether-co-maleic anhydride) nanoparticles as a new third-generation photosensitizer for anticancer photodynamic therapy

@inproceedings{Muehlmann2014AluminumphthalocyanineCA,
  title={Aluminum–phthalocyanine chloride associated to poly(methyl vinyl ether-co-maleic anhydride) nanoparticles as a new third-generation photosensitizer for anticancer photodynamic therapy},
  author={Lu{\'i}s Alexandre Muehlmann and Beatriz Chiyin Ma and Jo{\~a}o Paulo Figueir{\'o} Longo and Maria de F{\'a}tima Menezes Almeida Santos and Ricardo Bentes de Azevedo},
  booktitle={International journal of nanomedicine},
  year={2014}
}
Photodynamic therapy is generally considered to be safer than conventional anticancer therapies, and it is effective against different kinds of cancer. However, its clinical application has been significantly limited by the hydrophobicity of photosensitizers. In this work, a system composed of the hydrophobic photosensitizer aluminum-phthalocyanine chloride (AlPc) associated with water dispersible poly(methyl vinyl ether-co-maleic anhydride) nanoparticles is described. AlPc was associated with… CONTINUE READING
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