Aluminium lactate treatment of DQ12 quartz inhibits its ability to cause inflammation, chemokine expression, and nuclear factor-kappaB activation.

@article{Duffin2001AluminiumLT,
  title={Aluminium lactate treatment of DQ12 quartz inhibits its ability to cause inflammation, chemokine expression, and nuclear factor-kappaB activation.},
  author={Rodger Duffin and Peter Gilmour and Roel P F Schins and Anna Clouter and Keith Guy and David M. Brown and W. MacNee and Paul J. A. Borm and Ken Donaldson and Vicki Stone},
  journal={Toxicology and applied pharmacology},
  year={2001},
  volume={176 1},
  pages={10-7}
}
In 1997, an IARC Working Group classified quartz (crystalline silica) as a Group 1 lung carcinogen, but only in some industries, i.e., the quartz hazard is a variable entity. The reactivity of the quartz surface may underlie its ability to cause inflammation, and treatments that ameliorate this reactivity will reduce the quartz hazard. In this study we treated quartz (Q) with aluminium lactate (AL), a procedure that is reported to decrease the quartz hazard, and explored the effect this had on… CONTINUE READING