Alu pair exclusions in the human genome

  title={Alu pair exclusions in the human genome},
  author={George W. Cook and Miriam Konkel and James D Major and Jerilyn A. Walker and Kyudong Han and Mark A. Batzer},
  booktitle={Mobile DNA},
The human genome contains approximately one million Alu elements which comprise more than 10% of human DNA by mass. Alu elements possess direction, and are distributed almost equally in positive and negative strand orientations throughout the genome. Previously, it has been shown that closely spaced Alu pairs in opposing orientation (inverted pairs) are found less frequently than Alu pairs having the same orientation (direct pairs). However, this imbalance has only been investigated for Alu… CONTINUE READING