Altitude Acclimatization Alleviates the Hypoxia-Induced Suppression of Exogenous Glucose Oxidation During Steady-State Aerobic Exercise
@article{Young2018AltitudeAA, title={Altitude Acclimatization Alleviates the Hypoxia-Induced Suppression of Exogenous Glucose Oxidation During Steady-State Aerobic Exercise}, author={A. Young and C. Berryman and R. Kenefick and Allyson N. Derosier and L. Margolis and M. Wilson and Christopher T. Carrigan and N. E. Murphy and J. W. Carbone and J. Rood and S. Pasiakos}, journal={Frontiers in Physiology}, year={2018}, volume={9} }
This study investigated how high-altitude (HA, 4300 m) acclimatization affected exogenous glucose oxidation during aerobic exercise. Sea-level (SL) residents (n = 14 men) performed 80-min, metabolically matched exercise (V˙O2 ∼ 1.7 L/min) at SL and at HA < 5 h after arrival (acute HA, AHA) and following 22-d of HA acclimatization (chronic HA, CHA). During HA acclimatization, participants sustained a controlled negative energy balance (-40%) to simulate the “real world” conditions that… CONTINUE READING
Figures, Tables, and Topics from this paper
13 Citations
Effects of carbohydrate supplementation on aerobic exercise performance during acute high altitude exposure and after 22 days of acclimatization and energy deficit
- Medicine
- Journal of the International Society of Sports Nutrition
- 2020
- 2
Acute hypoxia reduces exogenous glucose oxidation, glucose turnover, and metabolic clearance rate during steady-state aerobic exercise.
- Chemistry, Medicine
- Metabolism: clinical and experimental
- 2019
- 2
Fuel Use during Exercise at Altitude in Women with Glucose–Fructose Ingestion
- Chemistry, Medicine
- Medicine and science in sports and exercise
- 2019
- 6
- Highly Influenced
- PDF
Isotope tracer assessment of exogenous glucose oxidation during aerobic exercise in hypoxia
- Chemistry, Medicine
- Physiological reports
- 2020
Nutritional strategies in an elite wheelchair marathoner at 3900 m altitude: a case report
- Medicine
- Journal of the International Society of Sports Nutrition
- 2019
- 4
Commentary on the effects of hypoxia on energy substrate use during exercise
- Medicine
- Journal of the International Society of Sports Nutrition
- 2019
- 4
Response: Commentary on the effects of hypoxia on energy substrate use during exercise
- Medicine
- Journal of the International Society of Sports Nutrition
- 2019
- 1
- PDF
Variability in human plasma volume responses during high‐altitude sojourn
- Chemistry, Medicine
- Physiological reports
- 2019
- 6
Appetite and energy intake responses to breakfast consumption and carbohydrate supplementation in hypoxia
- Medicine
- Appetite
- 2020
- PDF
Associations between the gut microbiota and host responses to high altitude
- Biology, Medicine
- American journal of physiology. Gastrointestinal and liver physiology
- 2018
- 10
References
SHOWING 1-10 OF 53 REFERENCES
Substrate utilization in sea level residents during exercise in acute hypoxia and after 4 weeks of acclimatization to 4100 m.
- Medicine, Chemistry
- Acta physiologica Scandinavica
- 2002
- 78
Increased dependence on blood glucose after acclimatization to 4,300 m.
- Chemistry, Medicine
- Journal of applied physiology
- 1991
- 239
The effect of altitude hypoxia on glucose homeostasis in men
- Chemistry, Medicine
- The Journal of physiology
- 1997
- 175
- Highly Influential
A comparison of substrate oxidation during prolonged exercise in men at terrestrial altitude and normobaric normoxia following the coingestion of 13C glucose and 13C fructose
- Chemistry, Medicine
- Physiological reports
- 2017
- 15
- Highly Influential
- PDF
Altitude and beta-blockade augment glucose utilization during submaximal exercise.
- Medicine
- Journal of applied physiology
- 1996
- 124
- Highly Influential
Carbohydrate feeding during exercise.
- Chemistry, Medicine
- International journal of sports medicine
- 1992
- 65
Fate of exogenous glucose during exercise of different intensities in humans.
- Chemistry, Medicine
- Journal of applied physiology: respiratory, environmental and exercise physiology
- 1982
- 90
- Highly Influential
Exogenous carbohydrate oxidation during ultraendurance exercise.
- Chemistry, Medicine
- Journal of applied physiology
- 2006
- 122
- Highly Influential
- PDF
Fatty acid oxidation is directly regulated by carbohydrate metabolism during exercise.
- Chemistry, Medicine
- The American journal of physiology
- 1997
- 276
Women at altitude: short-term exposure to hypoxia and/or alpha(1)-adrenergic blockade reduces insulin sensitivity.
- Medicine
- Journal of applied physiology
- 2001
- 84
- PDF