Alternatives to the tuberculin skin test: interferon-gamma assays in the diagnosis of mycobacterium tuberculosis infection.

@article{Pai2005AlternativesTT,
  title={Alternatives to the tuberculin skin test: interferon-gamma assays in the diagnosis of mycobacterium tuberculosis infection.},
  author={Madhukar Pai},
  journal={Indian journal of medical microbiology},
  year={2005},
  volume={23 3},
  pages={151-8}
}
  • Madhukar Pai
  • Published 2005 in Indian journal of medical microbiology
For nearly a century, there were no alternatives to the tuberculin skin test (TST) for diagnosing latent tuberculosis infection. Because of advances in immunology and genomics, for the first time, an alternative has emerged in the form of T cell based interferon-g (IFN-gamma) assays, a new generation of in vitro tests of cellular immunity. These assays measure cell mediated immune response by quantifying IFN-gamma released by T cells in response to stimulation by Mycobacterium tuberculosis… CONTINUE READING
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