Alternatives to animal testing: research, trends, validation, regulatory acceptance.

  title={Alternatives to animal testing: research, trends, validation, regulatory acceptance.},
  author={Jane Huggins},
  volume={20 Suppl 1},
Current trends and issues in the development of alternatives to the use of animals in biomedical experimentation are discussed in this position paper. Eight topics are considered and include refinement of acute toxicity assays; eye corrosion/irritation alternatives; skin corrosion/irritation alternatives; contact sensitization alternatives; developmental/reproductive testing alternatives; genetic engineering (transgenic) assays; toxicogenomics; and validation of alternative methods. The… CONTINUE READING
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