Alternatively spliced variants of the regucalcin gene in various human normal and tumor tissues.

@article{Murata2014AlternativelySV,
  title={Alternatively spliced variants of the regucalcin gene in various human normal and tumor tissues.},
  author={Tomiyasu Murata and Masayoshi Yamaguchi},
  journal={International journal of molecular medicine},
  year={2014},
  volume={34 4},
  pages={1141-6}
}
Regucalcin plays a pivotal role as a suppressor protein in signal transduction in various cell types. The regucalcin gene, which is localized on the X chromosome, consists of 7 exons and 6 introns. Decreased liver regucalcin gene expression has been suggested to play a suppressive role in the development of hepatocellular carcinogenesis in animal models. This study was undertaken to determine the changes in regucalcin gene expression in various human normal and tumor tissues, including liver… CONTINUE READING