Alternatively spliced transcripts of Sparus aurata insulin-like growth factor 1 are differentially expressed in adult tissues and during early development.

@article{Tiago2008AlternativelyST,
  title={Alternatively spliced transcripts of Sparus aurata insulin-like growth factor 1 are differentially expressed in adult tissues and during early development.},
  author={Daniel Martins Tiago and Vincent Laiz{\'e} and Maria Leonor Cancela},
  journal={General and comparative endocrinology},
  year={2008},
  volume={157 2},
  pages={107-15}
}
Spliced variants of insulin-like growth factor 1 (IGF-1), a small peptide with a critical role in metabolism and growth, have been identified in various vertebrate species. However, despite recent functional data in mammalian systems suggesting specific roles (e.g. in muscle formation) for their pro-peptides and/or E domains, their function remains unclear. In this study, three alternatively spliced variants of Sparus aurata proIGF-1 (1a, 1b, and 1c) were identified and their expression… CONTINUE READING

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