Alternatively spliced isoforms of the rat eye sodium/calcium+potassium exchanger NCKX1.

@article{Poon2000AlternativelySI,
  title={Alternatively spliced isoforms of the rat eye sodium/calcium+potassium exchanger NCKX1.},
  author={Stephen Poon and Stephen A Leach and Xiao-fang Li and Jennifer E Tucker and Paul P M Schnetkamp and Jonathan Lytton},
  journal={American journal of physiology. Cell physiology},
  year={2000},
  volume={278 4},
  pages={C651-60}
}
We have investigated the structure, function, and expression of the rat eye sodium/calcium+potassium exchanger NCKX1. The sequence of independent rat NCKX1 clones and the analysis of rat eye mRNA by RT-PCR revealed a region of alternative splicing that comprised four exons and encoded a stretch of 113 amino acids near the beginning of the large cytosolic loop. In comparison with other NCKX1 molecules and the rat NCKX2 protein, rat NCKX1 was highly conserved within the hydrophobic regions but… CONTINUE READING