Alternatively Activated Macrophages in Types 1 and 2 Diabetes

  title={Alternatively Activated Macrophages in Types 1 and 2 Diabetes},
  author={Arlett F Espinoza-Jim{\'e}nez and Alberto N Pe{\'o}n and Luis I Terrazas},
  booktitle={Mediators of inflammation},
Macrophages are innate immune cells derived from monocytes, which, in turn, arise from myeloid precursor cells in the bone marrow. Macrophages have many important roles in the innate and adaptive immune response, as well as in tissue homeostasis. Two major populations have been defined: The classically activated macrophages that respond to intracellular pathogens by secreting proinflammatory cytokines and reactive oxygen species and alternatively activated macrophages which are induced during… CONTINUE READING