Alternative translation initiation in immunity: MAVS learns new tricks.

Abstract

Translational control of gene expression contributes to various aspects of immune function [1]. Recent results by Brubaker et al. [2] show how alternative translation initiation produces distinct isoforms of Mitochondrial Antiviral Signaling (MAVS), an adaptor protein associated with RIG-I and MDA5 that possess unique immunomodulatory properties. 
DOI: 10.1016/j.it.2014.03.005

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Cite this paper

@article{Ivanov2014AlternativeTI, title={Alternative translation initiation in immunity: MAVS learns new tricks.}, author={Pavel Ivanov and Paul Anderson}, journal={Trends in immunology}, year={2014}, volume={35 5}, pages={188-9} }