Alternative trans-splicing: a novel mode of pre-mRNA processing.

@article{Horiuchi2006AlternativeTA,
  title={Alternative trans-splicing: a novel mode of pre-mRNA processing.},
  author={Takayuki Horiuchi and Toshiro Aigaki},
  journal={Biology of the cell},
  year={2006},
  volume={98 2},
  pages={135-40}
}
Alternative splicing is an important process contributing to proteome diversity without involving an increase in the number of genes. In some cases, alternative splicing is carried out under 'trans-mode', called alternative trans-splicing, in which exons located on separate pre-mRNA molecules are selectively joined to produce mature mRNAs encoding proteins with distinct structures and functions. However, it is not known how widespread or how frequently trans-splicing occurs in vivo. Recently… CONTINUE READING

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