Alternative splicing of the Evi-1 zinc finger gene generates mRNAs which differ by the number of zinc finger motifs.

@article{Bordereaux1990AlternativeSO,
  title={Alternative splicing of the Evi-1 zinc finger gene generates mRNAs which differ by the number of zinc finger motifs.},
  author={Didier Bordereaux and Serge Fichelson and Pierre E. Tambourin and Sylvie Gisselbrecht},
  journal={Oncogene},
  year={1990},
  volume={5 6},
  pages={925-7}
}
Evi-1 is a common integration site for endogenous ecotropic virus in myeloid leukemias of the AKXD mouse strain. This gene encodes a zinc finger protein with ten finger motifs. Myeloblastic leukemias obtained after infection with F-MuLV frequently exhibit proviral integration in the Fim-3 region which is genetically linked to Evi-1. This proviral integration always results in the expression of two mRNA transcripts, 5.7 kb and 4.7 kb long. We isolated two classes of cDNAs from a myeloblastic… CONTINUE READING

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