Alternative splicing generates two isoforms of the beta3-adrenoceptor which are differentially expressed in mouse tissues.

@article{Evans1998AlternativeSG,
  title={Alternative splicing generates two isoforms of the beta3-adrenoceptor which are differentially expressed in mouse tissues.},
  author={Bronwyn Anne Evans and Maria Papaioannou and Stanley Hamilton and Roger James Summers},
  journal={British journal of pharmacology},
  year={1998},
  volume={127 6},
  pages={
          1525-31
        }
}
The beta3-adrenoceptor (AR) differs from the beta1-AR and beta2-ARs in having introns within and downstream of the coding block. This study demonstrates two splice variants of the mouse beta3-AR which differ within the coding region. Reverse transcription/polymerase chain reaction with intron-spanning primers was used to demonstrate the splice variant of the mouse beta3-adrenoceptor. The novel beta3b-AR has 17 amino acids encoded by exon 2 (SSLLREPRHLYTCLGYP) which differ from the 13 in the… CONTINUE READING

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