Alternative splicing and promoter use in TFII-I genes.

  title={Alternative splicing and promoter use in TFII-I genes.},
  author={Aleksandr V. Makeyev and Dashzeveg Bayarsaihan},
  volume={433 1-2},
TFII-I proteins are ubiquitously expressed transcriptional factors involved in both basal transcription and signal transduction activation or repression. TFII-I proteins are detected as early as at two-cell stage and exhibit distinct and dynamic expression patterns in developing embryos as well as mark regional variation in the adult mouse brain. Analysis of atypical small and rare chromosomal deletions at 7q11.23 points to TFII-I genes (GTF2I and GTF2IRD1) as the prime candidates responsible… CONTINUE READING