Alternative pre-mRNA splicing in the human system: unexpected role of repetitive sequences as regulatory elements.

Abstract

Alternative splicing is a process by which multiple messenger RNAs (mRNAs) are generated from a single pre-mRNA, resulting in functionally distinct protein products. This is accomplished by the differential recognition of splice sites in the pre-mRNA, often regulated in a tissue- or development-specific manner. Alternative splicing constitutes not only an… (More)

Topics

  • Presentations referencing similar topics