Alternative pathway activation of the complement system in preterm infants with early onset infection.

@article{Zilow1997AlternativePA,
  title={Alternative pathway activation of the complement system in preterm infants with early onset infection.},
  author={Eugen P. Zilow and W Hauck and O. Linderkamp and Gertrud Zilow},
  journal={Pediatric research},
  year={1997},
  volume={41 3},
  pages={334-9}
}
The increased incidence of infection in preterm neonates has been related in part to their relative deficiency of most complement components, because complement is known to participate in the defense against bacterial and viral infections. In a prospective study, complement activation products were determined in 52 preterm infants. Twenty preterm infants suffered from proven early onset infection, 11 infants were presumed to suffer from infection, which could not be confirmed. Twenty-one… CONTINUE READING