Alternative origins of stroma in normal organs and disease.

@article{Kolonin2012AlternativeOO,
  title={Alternative origins of stroma in normal organs and disease.},
  author={Mikhail G Kolonin and Kurt William Evans and Sendurai A Mani and Richard H Gomer},
  journal={Stem cell research},
  year={2012},
  volume={8 2},
  pages={
          312-23
        }
}
Stromal fibroblasts are a new prospective drug target. Mesenchymal stromal cells (MSCs) and monocyte-derived stromal cells, also known as fibrocytes, are distinct fibroblastic populations derived from separate lineages. Mesenchymal and myeloid fibroblast progenitors are multipotent, serve as progenitor cells in animal models, and are implicated in several diseases. In addition, epithelial-mesenchymal transition (EMT) has been established as a mechanism for generation of stromal cells. Organ… CONTINUE READING
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