Alternative forms of the scavenger receptor BI (SR-BI).

  title={Alternative forms of the scavenger receptor BI (SR-BI).},
  author={Nancy R. Webb and Willem J. S. de Villiers and Patrick Mc Connell and Frederick C. de Beer and Deneys R. van der Westhuyzen},
  journal={Journal of lipid research},
  volume={38 7},
The class B, type I scavenger receptor has been implicated as a receptor for high density lipoprotein (HDL). We have isolated a murine cDNA clone encoding an alternative form of SR-BI that differs in the putative cytoplasmic domain of the receptor. This variant form, likely the result of alternative mRNA splicing, is designated SR-BI.2. SR-BI.2 mRNA was detected in mouse tissues known to express SR-BI and tissue-specific differences in the relative abundance of SR-BI.2 were apparent. In mouse… CONTINUE READING

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