Alternative Medicine in Neuropathic Pain Opioids in the Spinal Cord and Central Sensitization Spinothalamic Tract Neurons, Role of Nitric Oxide Long-Term Potentiation and Long-Term Depression in the Spinal Cord

Abstract

This is a long-lasting increase in synaptic efficacy resulting from repetitive activation of the synapse. This process was first described in hippocampus, whereby high-frequency stimulation of afferent pathways leads to a potentiated post-synaptic response that can last for hours to days. It is a form of activity-dependent plasticity. LTPmay increase the… (More)

Topics

Cite this paper

@inproceedings{Sandkhler2007AlternativeMI, title={Alternative Medicine in Neuropathic Pain Opioids in the Spinal Cord and Central Sensitization Spinothalamic Tract Neurons, Role of Nitric Oxide Long-Term Potentiation and Long-Term Depression in the Spinal Cord}, author={J{\"{u}rgen Sandk{\"{u}hler}, year={2007} }