Alternative 5' exons and differential splicing regulate expression of protein 4.1R isoforms with distinct N-termini.

@article{Parra2003Alternative5E,
  title={Alternative 5' exons and differential splicing regulate expression of protein 4.1R isoforms with distinct N-termini.},
  author={Marilyn K Parra and Sherry L. Gee and Mark J. Koury and Narla Mohandas and J. G. Conboy},
  journal={Blood},
  year={2003},
  volume={101 10},
  pages={4164-71}
}
Among the alternative pre-mRNA splicing events that characterize protein 4.1R gene expression, one involving exon 2' plays a critical role in regulating translation initiation and N-terminal protein structure. Exon 2' encompasses translation initiation site AUG1 and is located between alternative splice acceptor sites at the 5' end of exon 2; its inclusion… CONTINUE READING