Alternating hepatic intra-arterial floxuridine and fluorouracil: a less toxic regimen for treatment of liver metastases from colorectal cancer.

Abstract

Hepatic intra-arterial (HIA) infusion of floxuridine (FUDR) via an implanted pump has shown promise in the treatment of colorectal cancer metastasized to the liver. However, the potential benefit of this therapy may be offset by the high incidence of treatment-limiting biliary toxicity. Although weekly HIA bolus of fluorouracil (5-FU) is effective against… (More)

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Cite this paper

@article{Stagg1991AlternatingHI, title={Alternating hepatic intra-arterial floxuridine and fluorouracil: a less toxic regimen for treatment of liver metastases from colorectal cancer.}, author={Robert J. Stagg and Alan Paul Venook and Judy L. Chase and Barbara J Lewis and Robert S. Warren and Mee Sook Roh and Sean J. Mulvihill and B J Grobman and Anthony A. Rayner and David C. Hohn}, journal={Journal of the National Cancer Institute}, year={1991}, volume={83 6}, pages={423-8} }