Alternating hemiplegia of childhood or familial hemiplegic migraine? A novel ATP1A2 mutation.

@article{Swoboda2004AlternatingHO,
  title={Alternating hemiplegia of childhood or familial hemiplegic migraine? A novel ATP1A2 mutation.},
  author={Kathryn J Swoboda and Emmanuel Kanavakis and Athina Xaidara and Justine E. Johnson and Mark F. Leppert and Mylynda B Schlesinger-Massart and Louis J. Pt{\'a}cek and Kenneth Silver and Sotiris Youroukos},
  journal={Annals of neurology},
  year={2004},
  volume={55 6},
  pages={884-7}
}
Alternating hemiplegia of childhood (AHC) is typically distinguished from familial hemiplegic migraine (FHM) by infantile onset of the characteristic symptoms and high prevalence of associated neurological deficits that become increasingly obvious with age. Expansion of the clinical spectrum in FHM recently has begun to blur the distinction between these disorders. We report a novel ATP1A2 mutation in a kindred with features that bridge the phenotypic spectrum between AHC and FHM syndromes… CONTINUE READING