Alternating Modulation of Subthalamic Nucleus Beta Oscillations during Stepping

@inproceedings{Fischer2018AlternatingMO,
  title={Alternating Modulation of Subthalamic Nucleus Beta Oscillations during Stepping},
  author={Petra Fischer and Chiung Chu Chen and Ya-Ju Chang and Chien-Hung Yeh and Alek Pogosyan and Damian Marc Herz and Binith J Cheeran and Alexander L. Green and Tipu Z. Aziz and Jonathan Hyam and Simon Little and Thomas Foltynie and Patricia Dowsey Limousin and Ludvic U. Zrinzo and Harutomo Hasegawa and Michael Anthony Samuel and Keyoumars Ashkan and Peter Brown and Huiling Tan},
  booktitle={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2018}
}
Gait disturbances in Parkinson's disease are commonly refractory to current treatment options and majorly impair patient's quality of life. Auditory cues facilitate gait and prevent motor blocks. We investigated how neural dynamics in the human subthalamic nucleus of Parkinsons's disease patients (14 male, 2 female) vary during stepping and whether rhythmic auditory cues enhance the observed modulation. Oscillations in the beta band were suppressed after ipsilateral heel strikes, when the… CONTINUE READING
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