Alternate neuromuscular target selection following the loss of single muscle fibers in Drosophila.

@article{Cash1992AlternateNT,
  title={Alternate neuromuscular target selection following the loss of single muscle fibers in Drosophila.},
  author={Susan Cash and Akira Chiba and Haig Keshishian},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={1992},
  volume={12 6},
  pages={2051-64}
}
The Drosophila embryonic and larval body wall consists of a simple array of segmental muscle fibers, innervated in a precise manner by identified neurons. During development motoneurons were forced to find alternate targets following the selective deletion of a single muscle fiber, the pleural internal oblique #5. We used backfills, intracellular dyefills, and immunocytochemistry in embryos and larvae to characterize the normal motoneurons to the fiber. Deleting the fiber using either a genetic… CONTINUE READING

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