Alternate-day dosing of itraconazole in healthy adult cats.

  title={Alternate-day dosing of itraconazole in healthy adult cats.},
  author={Sydney M. Middleton and Amy Kubier and Levent Dirikolu and Mark G Papich and Mark A. Mitchell and Stanley I Rubin},
  journal={Journal of veterinary pharmacology and therapeutics},
  volume={39 1},
The current available formulations of itraconazole are not ideal for dosing in cats. The capsular preparation often does not allow for accurate dosing, the oral solution is difficult to administer and poorly tolerated, and the bioavailability of compounded formulations has been shown to be poor in other species. The aim of this study was to evaluate every other day dosing of 100 mg itraconazole capsule in healthy adult cats. Ten healthy adult cats received a 100 mg capsule of itraconazole… CONTINUE READING