Altered visual function and interneuron survival in Atrx knockout mice: inference for the human syndrome.

@article{Medina2009AlteredVF,
  title={Altered visual function and interneuron survival in Atrx knockout mice: inference for the human syndrome.},
  author={Chantal F Medina and Chantal J. Mazerolle and Yaping Wang and Nathalie G B{\'e}rub{\'e} and Stuart Coupland and Richard J. Gibbons and Valerie A Wallace and David J Picketts},
  journal={Human molecular genetics},
  year={2009},
  volume={18 5},
  pages={966-77}
}
ATRX is an SWI/SNF-like chromatin remodeling protein that is mutated in several X-linked mental retardation syndromes, including the ATR-X syndrome. In mice, Atrx expression is widespread and attempts to understand its function in brain development are hampered by the lethality associated with ubiquitous or forebrain-restricted ablation of this gene. One way to circumvent this problem is to study its function in a region of the brain that is dispensable for long-term survival of the organism… CONTINUE READING

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