Altered vaginal microbiota are associated with perinatal mother-to-child transmission of HIV in African women from Burkina Faso.

BACKGROUND Mother-to-child transmission (MTCT) of HIV remains a significant problem in resource-limited settings, despite the advent of antiretroviral therapies. Because perturbations in vaginal microbial communities are associated with sexual transmission of HIV, we determined whether perinatal MTCT is associated with the vaginal microbiotas of HIV… (More)