Altered tract-specific white matter microstructure is related to poorer cognitive performance: The Rotterdam Study

@article{Cremers2016AlteredTW,
  title={Altered tract-specific white matter microstructure is related to poorer cognitive performance: The Rotterdam Study},
  author={Lotte G. M. Cremers and Marius de Groot and Albert Hofman and Gabriel P. Krestin and Aad van der Lugt and Wiro J. Niessen and Meike W. Vernooij and Mohammad A Ikram},
  journal={Neurobiology of Aging},
  year={2016},
  volume={39},
  pages={108-117}
}
White matter microstructural integrity has been related to cognition. Yet, the potential role of specific white matter tracts on top of a global white matter effect remains unclear, especially when considering specific cognitive domains. Therefore, we determined the tract-specific effect of white matter microstructure on global cognition and specific cognitive domains. In 4400 nondemented and stroke-free participants (mean age 63.7 years, 55.5% women), we obtained diffusion magnetic resonance… CONTINUE READING
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