Altered tissue properties induce changes in cancellous bone architecture in aging and diseases.

@article{Linden2004AlteredTP,
  title={Altered tissue properties induce changes in cancellous bone architecture in aging and diseases.},
  author={Jacqueline C. van der Linden and Jamie S. Day and J. A. N. Verhaar and Harrie Weinans},
  journal={Journal of biomechanics},
  year={2004},
  volume={37 3},
  pages={367-74}
}
The mechanical properties of cancellous bone depend on its architecture and the tissue properties of the mineralized matrix. The architecture is continuously adapted to external loads. In this paper, it was assumed that changes in tissue properties leading to changes in tissue deformation can induce adaptation of the architecture. We asked whether changes in cancellous bone architecture with aging and in e.g. early osteoarthrosis can be explained from changes in tissue properties. This was… CONTINUE READING

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