Altered tissue behavior of a non-aneurysmal descending thoracic aorta in the mouse model of Marfan syndrome

@article{Haskett2011AlteredTB,
  title={Altered tissue behavior of a non-aneurysmal descending thoracic aorta in the mouse model of Marfan syndrome},
  author={Darren G. Haskett and Jefferson J. Doyle and Connie Gard and Hwu dau rw Chen and Corbie Ball and Mark A. Estabrook and Alejandra C. Encinas and Harry C. Dietz and Urs Utzinger and Jonathan P. Vande Geest and Mohamad Azhar},
  journal={Cell and Tissue Research},
  year={2011},
  volume={347},
  pages={267-277}
}
Aortic aneurysm is predominantly found in the ascending aorta in patients with Marfan syndrome (MFS). However, descending aortic disease has emerged as a problem since people are living longer because of improved medical and surgical management of the ascending aorta. Diagnostic procedures before disease onset and the mechanisms involved in the transition of normal aortic tissue to aneurysm remain unclear. We determined signs of descending aortic disease before disease onset in mice with a… 

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