Altered temporal difference learning in bulimia nervosa.

  title={Altered temporal difference learning in bulimia nervosa.},
  author={Guido K. W. Frank and Jeremy R. Reynolds and Megan E. Shott and Randall C. O'Reilly},
  journal={Biological psychiatry},
  volume={70 8},
BACKGROUND The neurobiology of bulimia nervosa (BN) is poorly understood. Recent animal literature suggests that binge eating is associated with altered brain dopamine (DA) reward function. In this study, we wanted to investigate DA-related brain reward learning in BN. METHODS Ill BN (n = 20, age: mean = 25.2, SD = 5.3 years) and healthy control women (CW) (n = 23, age: mean = 27.2, SD = 6.4 years) underwent functional magnetic resonance brain imaging together with application of a DA-related… CONTINUE READING
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