Altered sodium pump alpha and gamma subunit gene expression in nephron segments from hypertensive rats.

@article{Hayward1999AlteredSP,
  title={Altered sodium pump alpha and gamma subunit gene expression in nephron segments from hypertensive rats.},
  author={Alexander L Hayward and Cruz A D Hinojos and Barbara W Nurowska and Aveline Hewetson and Sandra Sabatini and Peter J. Oefner and P. A. Doris},
  journal={Journal of hypertension},
  year={1999},
  volume={17 8},
  pages={1081-7}
}
OBJECTIVE To determine the qualitative and quantitative expression of alpha and gamma sodium pump subunits in whole kidney and nephron segment RNA from Sprague Dawley rats, spontaneously hypertensive rats (SHR) and Wistar-Kyoto (WKY) rats. DESIGN A novel reverse transcription polymerase chain reaction technique was devised which provides accurate and precise measurement of the number of molecules of specific transcript abundance, a measurement of gene expression. This allows the quantitative… CONTINUE READING

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