Altered retinoic acid receptors.

  • Hugues de Thé
  • Published 1996 in
    FASEB journal : official publication of the…
Structurally and functionally altered retinoic acid receptors have been associated with rare human neoplasms: acute promyelocytic leukemia and hepatocellular carcinoma. Whereas the retinoic acid receptor beta (RARbeta) rearrangement in hepatocellular carcinoma is unique, in acute promyelocytic leukemia (APL), RARalpha fusion to the promyelocytic leukemia… CONTINUE READING