Altered reactivity of human cerebral arteries after subarachnoid hemorrhage.

  title={Altered reactivity of human cerebral arteries after subarachnoid hemorrhage.},
  author={Hisashi Onoue and Nobuyoshi Kaito and Masatoshi Akiyama and Masato Tomii and Shogo Tokudome and Tsukasa Abe},
  journal={Journal of neurosurgery},
  volume={83 3},
To investigate the effects of subarachnoid hemorrhage (SAH) on the responsiveness of human cerebral arteries to vasoactive substances, the authors measured the isometric tension generated in helical strips of basilar and middle cerebral arteries isolated from human cadavers. Contractions caused by KCl, prostaglandin F2 alpha, noradrenaline, and serotonin were reduced in arteries obtained from cadavers with aneurysmal SAH damage and compared to those obtained from cadavers with no indication of… CONTINUE READING


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