Altered number of diaphorase (NOS) positive neurons in the hypothalamus of rats with heart failure.

@article{Zhang1998AlteredNO,
  title={Altered number of diaphorase (NOS) positive neurons in the hypothalamus of rats with heart failure.},
  author={Kun Zhang and Irving H. Zucker and Kaushik P. Patel},
  journal={Brain research},
  year={1998},
  volume={786 1-2},
  pages={219-25}
}
Recently, we have demonstrated a decreased neuronal isoform of nitric oxide synthase (nNOS) message in the hypothalamus of rats with heart failure (HF). The purpose of this study was to determine the changes in NADPH-diaphorase (a commonly used marker for neuronal NOS activity) positive neurons in specific hypothalamic sites of rats with HF. After a standard histochemical protocol, NOS positive neurons were measured in paraventricular nucleus (PVN), supraoptic nucleus (SON), median preoptic… CONTINUE READING

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