Altered nitric oxide synthase immunoreactivity in the brain of stroke-prone spontaneously hypertensive rats

Abstract

To obtain information about the role of nitric oxide (NO) in the development of hypertensive cerebral lesions, we used immunohistochemical methods to study the distribution and level of nitric oxide synthase (NOS) in the brain of stroke-prone spontaneously hypertensive rats (SHRSPs). The early changes in the brain of SHRSPs were petechiae, edema and massive… (More)
DOI: 10.1007/s004010050499

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