Altered neurotransmitter expression profile in the ganglionic bowel in Hirschsprung's disease.

@article{Coyle2016AlteredNE,
  title={Altered neurotransmitter expression profile in the ganglionic bowel in Hirschsprung's disease.},
  author={D. Coyle and A. O'donnell and J. Gillick and P. Puri},
  journal={Journal of pediatric surgery},
  year={2016},
  volume={51 5},
  pages={
          762-9
        }
}
PURPOSE Despite having optimal pull-through (PT) surgery for Hirschsprung's disease (HSCR), many patients experience persistent bowel symptoms with no mechanical/histopathological cause. Murine models of HSCR suggest that expression of key neurotransmitters is unbalanced proximal to the aganglionic colonic segment. We aimed to investigate expression of key enteric neurotransmitters in the colon of children with HSCR. METHODS Full-length PT specimens were collected fresh from children with… Expand
Resection margin histology may predict intermediate-term outcomes in children with rectosigmoid Hirschsprung disease
Reducing Underdiagnosis of Hirschsprung-Associated Enterocolitis: A Novel Scoring System.
The role of gasotransmitters in neonatal physiology.

References

SHOWING 1-10 OF 26 REFERENCES
Peptidergic nerves in Hirschsprung's disease and its allied disorders.
  • R. Tomita, K. Munakata, Y. Kurosu
  • Medicine
  • European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie
  • 1994
Hirschsprung's disease
...
1
2
3
...