Altered neuronal gene expression in brain regions differentially affected by Alzheimer's disease: a reference data set.

@article{Liang2008AlteredNG,
  title={Altered neuronal gene expression in brain regions differentially affected by Alzheimer's disease: a reference data set.},
  author={Winnie S. Liang and Travis Dunckley and Thomas Gerald Beach and Andrew Grover and Diego Mastroeni and Keri E. Ramsey and Richard J. Caselli and Walter Kukull and Daniel T McKeel and John C. Morris and Christine M. Hulette and Donald E. Schmechel and Eric M. Reiman and Joseph Rogers and Dietrich A. Stephan},
  journal={Physiological genomics},
  year={2008},
  volume={33 2},
  pages={240-56}
}
Alzheimer's Disease (AD) is the most widespread form of dementia during the later stages of life. If improved therapeutics are not developed, the prevalence of AD will drastically increase in the coming years as the world's population ages. By identifying differences in neuronal gene expression profiles between healthy elderly persons and individuals diagnosed with AD, we may be able to better understand the molecular mechanisms that drive AD pathogenesis, including the formation of amyloid… CONTINUE READING
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