Altered monocyte-derived dendritic cell function in patients on hemodialysis: a culprit for underlying impaired immune responses

@article{Choi2011AlteredMD,
  title={Altered monocyte-derived dendritic cell function in patients on hemodialysis: a culprit for underlying impaired immune responses},
  author={Hye Min Choi and Young Seok Woo and Myung Gyu Kim and Sang Kyung Jo and Wonyong Cho and Hyoung Kyu Kim},
  journal={Clinical and Experimental Nephrology},
  year={2011},
  volume={15},
  pages={546-553}
}
Patients with end-stage renal disease (ESRD) are known to have impaired immune function. Dendritic cells (DCs) are the major antigen-presenting cells that initiate primary immune responses, linking innate and adaptive immunity. Although suboptimal immune responses to vaccination, as frequently observed in ESRD patients, might suggest the presence of impaired DC function, the precise nature of altered DC function is not fully understood. In the current study, we compared the maturation status… CONTINUE READING