Altered microRNA and gene expression in the follicular fluid of women with polycystic ovary syndrome

@article{Roth2013AlteredMA,
  title={Altered microRNA and gene expression in the follicular fluid of women with polycystic ovary syndrome},
  author={Lauren W. Roth and Blair McCallie and Ruben Alvero and William B. Schoolcraft and Debra A. Minjarez and Mandy G. Katz-Jaffe},
  journal={Journal of Assisted Reproduction and Genetics},
  year={2013},
  volume={31},
  pages={355-362}
}
To determine if microRNAs are differentially expressed in the follicular fluid of women with PCOS compared to fertile oocyte donors and identify associated altered gene expression. Women undergoing IVF who met Rotterdam criteria for PCOS or who were fertile oocyte donors were recruited from a private IVF center. Individual follicle fluid was collected at the time of oocyte retrieval. MicroRNA analysis was performed using microarray and validated using real-time PCR on additional samples… CONTINUE READING