Altered miRNA expression in lung tissues of patients with chronic obstructive pulmonary disease

Chronic obstructive pulmonary disease (COPD) is a complex disorder characterized by airflow limitation. Epigenetic control affects gene expression in the lung, and microRNAs (miRNAs) are one of the primary types of epigenetic modifiers. In this study, lung tissues were obtained from 15 COPD patients and 11 subjects with normal lung function. RNA was… (More)