Altered meiotic regulation in oocytes from diabetic mice.

@article{Colton2002AlteredMR,
  title={Altered meiotic regulation in oocytes from diabetic mice.},
  author={Shannondoah A Colton and Galen M. Pieper and Stephen M Downs},
  journal={Biology of reproduction},
  year={2002},
  volume={67 1},
  pages={220-31}
}
In the present study, we have utilized a streptozotocin-induced diabetic mouse model to examine how the diabetic condition and different glucose concentrations affect several parameters of reproductive physiology. We report that oocyte maturation is altered under all experimental conditions examined. In cumulus cell-enclosed oocytes (CEO) from diabetic mice, spontaneous maturation was accelerated but the FSH-mediated delay of spontaneous maturation was suppressed. Higher glucose levels in the… CONTINUE READING
35 Extracted Citations
0 Extracted References
Similar Papers

Citing Papers

Publications influenced by this paper.
Showing 1-10 of 35 extracted citations

Similar Papers

Loading similar papers…