Altered map of visual space in the superior colliculus of mice lacking early retinal waves.

@article{MrsicFlogel2005AlteredMO,
  title={Altered map of visual space in the superior colliculus of mice lacking early retinal waves.},
  author={Thomas D. Mrsic-Flogel and Sonja B. Hofer and Claire J Creutzfeldt and Isabelle Clo{\"e}z-Tayarani and Jean-Pierre Changeux and Tobias Bonhoeffer and Mark H{\"u}bener},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2005},
  volume={25 29},
  pages={
          6921-8
        }
}
During the development of the mammalian retinocollicular projection, a coarse retinotopic map is set up by the graded distribution of axon guidance molecules. Subsequent refinement of the initially diffuse projection has been shown to depend on the spatially correlated firing of retinal ganglion cells. In this scheme, the abolition of patterned retinal activity is not expected to influence overall retinotopic organization, but this has not been investigated. We used optical imaging of intrinsic… CONTINUE READING

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