Altered macrophage-like functions of preadipocytes in inflammation and genetic obesity.

@article{Cousin2001AlteredMF,
  title={Altered macrophage-like functions of preadipocytes in inflammation and genetic obesity.},
  author={Beatrice Cousin and Mireille Andr{\'e} and Louis Casteilla and Luc P{\'e}nicaud},
  journal={Journal of cellular physiology},
  year={2001},
  volume={186 3},
  pages={380-6}
}
We recently demonstrated that preadipocytes exhibit functional features of macrophages, such as phagocytosis and anti-microbial activity, suggesting that preadipose cells could play a role in the inflammatory process or immune response. The aim of this study was to compare these functions of both macrophages and cells from stroma-vascular fraction (SVF) of the adipose tissue in two different situations, obesity and inflammation, characterized by alterations in immune responsiveness. We… CONTINUE READING