Altered mRNA expression of monoaminergic candidate genes in the blood of children with attention deficit hyperactivity disorder and autism spectrum disorder.

@article{Taurines2011AlteredME,
  title={Altered mRNA expression of monoaminergic candidate genes in the blood of children with attention deficit hyperactivity disorder and autism spectrum disorder.},
  author={Regina Taurines and Edna Gr{\"u}nblatt and Martin Schecklmann and Christina Schwenck and Laura Albantakis and Lennart Reefschl{\"a}ger and Susanne Walitza and Tobias Renner and Manfred Gerlach and Johannes Thome and Marcel Romanos},
  journal={The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry},
  year={2011},
  volume={12 Suppl 1},
  pages={104-8}
}
OBJECTIVES In absence of objective clinical characteristics the identification of peripheral biomarkers in neuropsychiatric disorders is highly relevant for the diagnostic process and an individualized therapy. We analyzed mRNA-expression of monoaminergic candidate genes (DRD4, DRD5, TPH1) in peripheral tissue of patients with attention deficit hyperactivity disorder (ADHD) and autism spectrum disorders (ASD), highly comorbid with ADHD, searching for possible molecular markers for these… CONTINUE READING