Altered intrarenal accumulation of mercury in uninephrectomized rats treated with methylmercury chloride.

@article{Zalups1992AlteredIA,
  title={Altered intrarenal accumulation of mercury in uninephrectomized rats treated with methylmercury chloride.},
  author={Rudolfs K. Zalups and Delon W. Barfuss and Paul J. Kostyniak},
  journal={Toxicology and applied pharmacology},
  year={1992},
  volume={115 2},
  pages={
          174-82
        }
}
  • Rudolfs K. Zalups, Delon W. Barfuss, Paul J. Kostyniak
  • Published in
    Toxicology and applied…
    1992
  • Chemistry, Medicine
  • We tested the hypothesis that the intrarenal accumulation of mercury in rats treated with methylmercury is altered significantly as a result of unilateral nephrectomy and compensatory renal growth. Renal accumulation of mercury was evaluated by radioisotopic techniques in both uninephrectomized (NPX) and sham-operated (SO) rats 1, 2, and 7 days after the animals received a nonnephrotoxic intravenous dose of methylmercury chloride (5 mg/kg Hg). At all times studied after the injection of the… CONTINUE READING

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