Altered imprinting of rat liver monoamine oxidase by o, p'-DDT and methoxychlor.


Neonatal administration of o,p'-DDT [1, 1, 1-trichloro-2-(o-chlorophenyl-2-(chlorophenyl)ethane] or methoxychlor resulted in elevated levels of sex-differentiated hepatic monoamine oxidase activities in adult rats, but not in prepubertal animals. Exposure to these hormonally active xenobiotics may have changed the brain hormone environment during the… (More)