Altered hippocampal-prefrontal activation in HIV patients during episodic memory encoding

  title={Altered hippocampal-prefrontal activation in HIV patients during episodic memory encoding},
  author={J. Mimi Boer Castelo and Scott J. Sherman and Maureen G. Courtney and Rebecca J. Melrose and Chantal E. Stern},
  pages={1688 - 1695}
Objective: To investigate the integrity of hippocampal-prefrontal circuitry during episodic encoding in patients with HIV. Methods: Functional MRI was used to observe changes in blood oxygenation level-dependent (BOLD) signal in 14 HIV-positive participants and 14 age- and education-matched control subjects while performing an episodic encoding task. Subjects also completed neuropsychological measures of attention and memory. Results: Behavioral results revealed no significant differences in… 

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