Altered hippocampal expression of glutamate receptors and transporters in GRM2 and GRM3 knockout mice

Abstract

Group II metabotropic glutamate receptors (mGluR2 and mGluR3, also called mGlu2 and mGlu3, encoded by GRM2 and GRM3, respectively) are therapeutic targets for several psychiatric disorders. GRM3 may also be a schizophrenia susceptibility gene. mGluR2-/- and mGluR3-/- mice provide the only unequivocal means to differentiate between these receptors, yet… (More)
DOI: 10.1002/syn.20553

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